Comparison

Chaetominine European Partner

Item no. HY-125136-100mg
Manufacturer MedChem Express
CASRN 918659-56-0
Amount 100 mg
Quantity options 100 mg 1 ea 5 mg
Category
Type Chemicals
Specific against other
Citations [1]Jiao RH, et al. Chaetominine, a cytotoxic alkaloid produced by endophytic Chaetomium sp. IFB-E015. Org Lett.
[2]Yao J, et al. Chaetominine reduces MRP1-mediated drug resistance via inhibiting PI3K/Akt/Nrf2 signaling pathway in K562/Adr human leukemia cells. Biochem Biophys Res Commun. 2016;473(4):867-873.
Smiles O[C@]1(C[C@@]2([H])N(C=NC3=CC=CC=C43)C4=O)[C@](N([C@H]5C)C2=O)([H])N(C5=O)C6=CC=CC=C16
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Alias (-)-Chaetominine
Shipping Condition Room temperature
Available
Manufacturer - Type
Natural Products
Manufacturer - Applications
Cancer-Kinase/protease
Shipping Temperature
Room Temperature
Molecular Weight
402.40
Product Description
Chaetominine is an alkaloidal metabolite. Chaetominine has cytotoxicity against human leukemia K562 and colon cancer SW1116 cell lines. Chaetominine reduces MRP1-mediated agent resistance via inhibiting PI3K/Akt/Nrf2 signaling pathway in K562/Adr human leukemia cells[1][2].
Manufacturer - Research Area
Cancer
Solubility
10 mM in DMSO
Manufacturer - Pathway
NF-κB; PI3K/Akt/mTOR
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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