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Pafolacianine

Pafolacianine

Item no.	HY-139579-10mg
Manufacturer	MedChem Express
CASRN	1628423-76-6
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Staining & Dyes
Type	Reagents
Specific against	other
Purity	99.04
Citations	[1]Jane J Keating, et, al. Intraoperative near-infrared fluorescence imaging targeting folate receptors identifies lung cancer in a large-animal model. Cancer. 2017 May 15;123(6):1051-1060.\|[2]Gul Z, et al. Pafolacianine, the magic wand of intraoperative imaging of folate-receptor positive ovarian cancer. Ann Transl Med. 2023 Oct 25;11(11):394.\|[3]Ishiwata T, et al. Transbronchial real-time lung tumor localization with folate receptor-targeted near-infrared molecular imaging: A proof of concept study in animal models. J Thorac Cardiovasc Surg. 2023 Jun;165(6):e240-e251.
Smiles	O=S(CCCCN1C2=CC=C(S(=O)(O)=O)C=C2C(C)(/C1=C/C=C3C(OC4=CC=C(C=C4)C[C@@H](C(O)=O)NC(C5=CC=C(C=C5)NCC(N=C67)=CNC6=NC(N)=NC7=O)=O)=C(CCC\3)/C=C\C8=[N+](C9=CC=C(S(=O)([O-])=O)C=C9C8(C)C)CCCCS(=O)(O)=O)C)(O)=O
ECLASS 10.1	42051003
ECLASS 11.0	42051003
UNSPSC	12000000
Alias	OTL 38
Shipping Condition	Room temperature
Available
Manufacturer - Type	Dye Reagents
Manufacturer - Targets	Fluorescent Dye
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	1326.49
Product Description	Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775 nm and emits at 794 to 796 nm[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 25 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Others
Clinical information	Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-139579-10mg-safety-datasheet.pdf