ER176

Item no.	HY-141804-100mg
Manufacturer	MedChem Express
CASRN	1373887-29-6
Amount	100 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.77
Citations	[1]Masahiro Fujita, et al. Comparison of four 11 C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios. EJNMMI Res. 2017 Oct 16;7(1):84.\|[2]Jason C Mixdorf, et al. Alternative strategies for the synthesis of [ 11 C]ER176 for PET imaging of neuroinflammation. Appl Radiat Isot. 2021 Sep 17;178:109954.
Smiles	O=C(C1=NC(C2=CC=CC=C2Cl)=C3C=CC=CC3=N1)N(C)[C@H](C)CC
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Biochemical Assay Reagents
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	353.85
Product Description	ER176 is a next generation PET radioligand for imaging 18 kDa translocator protein (TSPO), a biomarker for neuroinflammation[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Others
Clinical information	Phase 2

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HY-141804-100mg-safety-datasheet.pdf