Comparison

ALK5-IN-7 European Partner

Item no. HY-142949-100mg
Manufacturer MedChem Express
CASRN 2657720-07-3
Amount 100 mg
Quantity options 100 mg 1 ea
Category
Type Chemicals
Specific against other
Citations [1]Tang Feng, et al. Pyrazoles. Patent WO2021129621A1.
Smiles OC(C)(C)C1=NC=CC(C2=CC3=NC=CC(OC4=CN(C5CC5)N=C4C6CCOCC6)=C3S2)=C1
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Targets
TGF-β Receptor
Shipping Temperature
Room temperature
Molecular Weight
476.59
Product Description
ALK5-IN-7 is a potent inhibitor of ALK5. Transforming growth factor beta (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation and apoptosis through complex receptor signaling pathways on the cell surface in an autocrine, paracrine and endocrine manner. ALK5-IN-7 has the potential for the research of TGF-β-related diseases and conditions, including but not limited to tumors, fibrotic diseases, inflammatory diseases, autoimmune diseases, etc (extracted from patent WO2021129621A1, compound 4)[1].
Manufacturer - Research Area
Cancer; Inflammation/Immunology
Solubility
10 mM in DMSO
Manufacturer - Pathway
TGF-beta/Smad
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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