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HPK1-IN-29

HPK1-IN-29

Item no.	HY-143870-100mg
Manufacturer	MedChem Express
CASRN	2699604-50-5
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Jiang Lei, et al. Novel hpk1 inhibitors and methods of preparation and application thereof. Patent WO2021175270A1.
Smiles	N#CC1=CN=C2NC=C(C2=C1OC3=C(C=C(NC4=NCC5(CC5)CO4)C=C3F)F)C6=CC=C(F)C=C6
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	MAP4K
Shipping Temperature	Room temperature
Molecular Weight	489.45
Product Description	HPK1-IN-29 is a potent inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-29 enhances the body's anti-tumor immunity. HPK1-IN-29 has the potential for the research of immune-related diseases, especially tumor (extracted from patent WO2021175270A1, compound 38)[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	MAPK/ERK Pathway
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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