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Anti-inflammatory agent 11

Anti-inflammatory agent 11

Item no.	HY-144727-100mg
Manufacturer	MedChem Express
CASRN	63932-07-0
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Calixto SD, et al. Antimycobacterial and anti-inflammatory activities of thiourea derivatives focusing on treatment approaches for severe pulmonary tuberculosis. Bioorg Med Chem. 2022 Jan 1;53:116506.
Smiles	[H]N(C(N(NC(C1=CC=NC=C1)=O)[H])=S)CC2=CC=CC=C2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial; TNF Receptor
Shipping Temperature	Room temperature
Molecular Weight	286.35
Product Description	Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 11 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 1.3 and 6.9 μM, respectively. Anti-inflammatory agent 11 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 11 can be used for tuberculosis (TB) research[1].
Manufacturer - Research Area	Infection; Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection; Apoptosis
Isoform	TNFRSF5/CD40
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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