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(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine

(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine

Item no.	HY-147025-100mg
Manufacturer	MedChem Express
CASRN	2347517-69-3
Amount	100 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.06
Formula	C41H46N6O6S
Citations	[1]Method for dual-target construction of protac, and use thereof. WO2020119192A1.
Smiles	O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCC(NC(C4=CN=CC=C4)C5=CC6=CC=CC=C6O5)=O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	HIF/HIF Prolyl-Hydroxylase; PROTACs; TGF-beta/Smad
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	750.91
Product Description	(S, R, S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. (S, R, S)-AHPC-C2-amide-benzofuranylmethyl-pyridine has a multi-path anti-fibrosis function and a renal protection function for research of renal anemia[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO : ≥ 170 mg/mL
Manufacturer - Pathway	Metabolic Enzyme/Protease; PROTAC; Stem Cell/Wnt; TGF-beta/Smad
Clinical information	No Development Reported

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HY-147025-100mg-safety-datasheet.pdf