Comparison

Drinabant European Partner

Item no. HY-14788-100mg
Manufacturer MedChem Express
CASRN 358970-97-5
Amount 100 mg
Quantity options 100 mg 10 mg 1 ea 1 mg 25 mg 5 mg
Category
Type Chemicals
Specific against other
Purity 99.0
Citations [1]Andreas W Herling, et al. CB1 receptor antagonist AVE1625 affects primarily metabolic parameters independently of reduced food intake in Wistar rats. Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E826-32.|[2]Michaela Liebig, et al. Profiling of energy metabolism in olanzapine-induced weight gain in rats and its prevention by the CB1-antagonist AVE1625. Obesity (Silver Spring). 2010 Oct;18(10):1952-8.|[3]Mark D Black, et al. AVE1625, a cannabinoid CB1 receptor antagonist, as a co-treatment with antipsychotics for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in rodents. Psychopharmacology (Berl). 2011 May;215(1):149-63.
Smiles CS(=O)(N(C1CN(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)C1)C4=CC(F)=CC(F)=C4)=O
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Alias AVE1625
Shipping Condition Cool pack
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Metabolism-protein/nucleotide metabolism
Manufacturer - Targets
Cannabinoid Receptor
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Molecular Weight
497.38
Product Description
Drinabant (AVE1625) is an orally active CB1 receptor antagonist. Drinabant (AVE1625) inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-R and rCB1-R, respectively, and is ineffective for the hCB2-R[1].
Manufacturer - Research Area
Metabolic Disease
Solubility
DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway
GPCR/G Protein; Neuronal Signaling
Isoform
CB1; CB2
Clinical information
Phase 2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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