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Taurocholic acid (sodium)

Taurocholic acid (sodium)

Item no.	HY-N0545-5g
Manufacturer	MedChem Express
CASRN	145-42-6
Amount	5 g
Quantity options	10 mM/1 mL 1 ea 1 g 500 mg 5 g
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.14
Citations	[1]Caiyun Wang, et al. Effects of taurocholic acid on immunoregulation in mice. Int Immunopharmacol. 2013 Feb;15(2):217-22.\|[2]Xun Z,et al. Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function. Cell Mol Immunol. 2021 Feb;18(2):461-471. \|[3]Glaser S, et al. Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats. Dig Liver Dis. 2010 Oct;42(10):709-17. Adv Healthc Mater. 2024 Dec 4:e2402773.\|FASEB J. 2022 May;36(5):e22305.\|Int J Mol Sci. 2025 Feb 22;26(5):1899.\|Research Square Preprint. 2024 Feb 13.\|Sci Rep. 2024 Oct 31;14(1):26216.\|Adv Sci (Weinh). 2025 Feb 3:e2411719.\|Antiviral Res. 2019 Jun 27;169:104544.\|Food Funct. 2024 Apr 11.\|Food Funct. 2024 Sep 11.\|Int Immunopharmacol. 2024 Dec 10:145:113739.\|J Pharm Biomed Anal. 2025 Feb 25:259:116760.\|J Transl Med. 2024 Dec 20;22(1):1124.\|Nature. 2024 Dec 18.\|Placenta. 2024 Feb 8:148:20-30.\|Plant Commun. 2024 Nov 4:101181.\|Research (Wash D C). 2022 Nov 2;2022:9784081.\|Research Square Print. 2022 Aug.\|Science. 2024 Mar 22;383(6689):eadj4591.\|Biomolecules. 2022, 12(8), 1063.\|RSC Adv. 2018 8:8469-8483.\|SSRN. 2022 Jan 26.
Smiles	C[C@H](CCC(NCCS(=O)(O[Na])=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Sodium taurocholate,N-Choloyltaurine (sodium)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Endogenous Metabolite; VEGFR
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Molecular Weight	537.68
Product Description	Taurocholic acid sodium (Sodium taurocholate) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid sodium has immunoregulation effect[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: ≥ 100 mg/mL\|H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Isoform	Human Endogenous Metabolite; Microbial Metabolite
Clinical information	Phase 2

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HY-N0545-5g-safety-datasheet.pdf