Comparison

Concanamycin A European Partner

Item no. HY-N1724-1mg
Manufacturer MedChem Express
CASRN 80890-47-7
Amount 1 mg
Quantity options 100 ug 1 mg 25 ug 50 ug
Category
Type Molecules
Specific against other
Purity 99.0
Citations [1]Togashi K, et al. Concanamycin A, a vacuolar type H(+)-ATPase inhibitor, induces cell death in activated CD8(+) CTL. Cytotechnology. 1997 Nov;25(1-3):127-35.
[2]Eswarappa SM, et al. Folimycin (concanamycin A) inhibits LPS-induced nitric oxide production and reduces surface localization of TLR4 in murine macrophages. Innate Immun. 2008 Feb;14(1):13-24.
[3]Hines IN, et al. Impaired T cell-mediated hepatitis in peroxisome proliferator activated receptor alpha (PPARα)-deficient mice. Biol Res. 2018 Feb 15;51(1):5.
[4]Woo JT, et al. Isolation, characterization and biological activities of concanamycins as inhibitors of lysosomal acidification. J Antibiot (Tokyo). 1992 Jul;45(7):1108-16.
[5]Vaněk, Z., et al. Immunomodulators isolated from microorganisms. Folia Microbiol. 1991. 36:99–111.
Smiles C[C@H]([C@@](C[C@H]1O[C@@](O[C@H](C)[C@H]2OC(N)=O)([H])C[C@H]2O)(O[C@H](/C=C/C)[C@H]1C)O)[C@H](O)[C@@H]([C@](OC(/C(OC)=C/C(C)=C/[C@H]([C@@H](O)[C@H]3CC)C)=O)([H])[C@H](/C=C/C=C(C[C@H]([C@@H]3O)C)/C)OC)C
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias Antibiotic X 4357B; Folimycin; X 4357B
Shipping Condition Cool pack
Available
Manufacturer - Type
Natural Products
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
Antibiotic; Bacterial; Proton Pump
Shipping Temperature
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Molecular Weight
866.09
Product Description
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H+-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research[1]-[5].
Manufacturer - Research Area
Cancer; Infection; Inflammation/Immunology
Solubility
DMSO : ≥ 10 mg/mL|Methanol : 10 mg/mL (ultrasonic; warming)
Manufacturer - Pathway
Anti-infection; Membrane Transporter/Ion Channel
Isoform
Macrolide
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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