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Z-Gly-Gly-Arg-AMC

Z-Gly-Gly-Arg-AMC

Item no.	HY-P0019-100mg
Manufacturer	MedChem Express
CASRN	66216-78-2
Amount	100 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 1 ea 50 mg 5 mg
Category	Reagents & Chemicals Staining & Dyes
Type	Reagents
Specific against	other
Purity	99.90
Citations	[1]Mothukuri GK, et al. Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries. Chem Sci. 2020 Jun 26;11(30):7858-7863. \|[2]Tarandovskiy ID, et al. Antiplatelet agents can promote two-peaked thrombin generation in platelet rich plasma: mechanism and possible applications. PLoS One. 2013;8(2):e55688. \|[3]Machlus KR, et al. Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram. Thromb Haemost. 2009 Nov;102(5):936-44. Int J Biol Macromol. 2019 Aug 1;134:622-630. \|Int J Biol Macromol. 2019 Sep 15;137:261-269.\|Phytochemistry. 2019 Jun 14;165:112025.\|Acta Pharmacol Sin. 2024 Jun 24.\|Bioorg Chem. 2019 Nov;92:103199. \|Chem Biol Interact. 2023 Apr 18;110501.\|J Mater Chem B. 2017 Oct 14;5(38):7876-7884. \|RSC Adv. 2020, 10(7):3626-3635.\|Spectrochim Acta A Mol Biomol Spectrosc. 6 August 2021, 120250.
Smiles	O=C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(NC1=CC=C(C(C)=CC(O2)=O)C2=C1)=O)=O)=O)OCC3=CC=CC=C3
ECLASS 10.1	42051003
ECLASS 11.0	42051003
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Dye Reagents
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Fluorescent Dye; Thrombin
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Molecular Weight	579.60
Product Description	Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm)[1][2].
Manufacturer - Research Area	Cardiovascular Disease
Solubility	H2O: 40 mg/mL (ultrasonic; warming)\|DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Others
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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