MASM7

Item no.	HY-W187305-100mg
Manufacturer	MedChem Express
CASRN	920868-45-7
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.85
Citations	[1]Emmanouil Zacharioudakis, et al. Modulating mitofusins to control mitochondrial function and signaling. Nat Commun. 2022 Jul 7;13(1):3775.
Smiles	O=C(N)C1=C(SC2=C1CCC2)NC(C(C)SC3=NN=C(C4CC4)N3C5=CC=CC=C5)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Mitochondrial Metabolism
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	453.58
Product Description	MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 μM[1].
Manufacturer - Research Area	Others
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-W187305-100mg-safety-datasheet.pdf