Comparison

P62-mediated mitophagy inducer

Item no. MOLN-M12772-50mg
Manufacturer Molnova
CASRN 1809031-84-2
Amount 50 mg
Quantity options 100 mg 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Chemicals
Specific against other
Purity >98% (HPLC)
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Available
Storage Conditions
(-20°C)
Molecular Weight
392, 156
Brief description
P62-mediated mitophagy inducer (PMI) is a small molecule p62-mediated mitophagy inducer that activates mitophagy without recruiting Parkin or collapsing membrane potential and retains activity in cells devoid of a fully functional PINK1/Parkin pathway; induces doubling NQO1 activity at 1 uM, and upregulates Nrf2 and ARE-dependent antioxidant genes; increases the expression and signaling of the autophagic adaptor molecule P62/SQSTM1 and forces mitochondria into autophagy; disrupts the Nrf2-Keap1 interaction.
Note
Research use only, not for human use.
Stability
≥ 2 years
Receptor
Mitophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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