ML-180

Item no.	MOLN-M22607-10mg
Manufacturer	Molnova
CASRN	863588-32-3
Amount	10 mg
Quantity options	100 mg 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Purity	>98% (HPLC)
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Storage Conditions	(-20°C)
Molecular Weight	388.89
Brief description	ML-180 is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 µM) .ML-180 (0.5-5 µM; 24 hours) shows a significant inhibition of cyclin-D1 and cyclin-E1 expression in hepatic cells, but has little effect on repression in SK-OV-3 cells[2]. ML-180 (5 µM; 24 hours) leads to a rapid decrease of LRH-1 expression and efficiently represses endogenous LRH-1 signaling.
Note	Research use only, not for human use.
Stability	≥ 2 years
Receptor	orphan nuclear receptor NR5A2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

MOLN-M22607-10mg.pdf

MOLN-M22607-10mg-datasheet.pdf

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Amount: 10 mg

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