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Anti-Succinyllysine Antibody Conjugated Agarose Beads

Anti-Succinyllysine Antibody Conjugated Agarose Beads

Item no.	PTM-402
Manufacturer	PTM Biolabs
Amount	500 ul
Category	Reagents & Chemicals Nanoparticles Beads & Resins
Type	Antibody Conjugated Beads
Format	Liquid
Applications	IA
Specific against	other
Isotype	IgG
Conjugate/Tag	Agarose
Dry ice	Yes
Citations	Ruilong Liu, et al. Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis. Cell Metabolism, 2024. https://www.cell.com/cell-metabolism/abstract/S1550-4131(24)00451-0.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	41105507
Alias	Ksu
Shipping Condition	Dry ice
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Applications	IAP
Manufacturer - Category	Pan PTM Antibodies
Shipping Temperature	Cold packs / dry ice
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight	Multiple
Stability	Stable for 12 months from date of receipt.
Manufacturer - Research Area	Post-Translational Modificaiton
Manufacturer - Reactivity	All
Product description	Lysine succinylation is an important reversible modification, and plays significant roles i nmany cellular processes. Systematical screening of lysine succinylated substrates in various cellular pathological and physiological conditions is a fundamental mission in lysine succinylation biology.To address this, the affinity chromatography with Anti-Succinyllysine Antibody Conjugated Agarose Beads followed by MS/MS identification is viewed as the most preferable and efficient method.
Manufacturer - Specificity	With the immobilization of highly specific anti-succinyllysine antibody, the Anti-Succinyllysine Antibody Conjugated Agarose Beads selectively capture peptides/proteins bearing succinyllysine residues, but do not cross-react with the peptides/proteins bearing other structurally similar modified residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine succinylation.
Formula	Antibody conjugated agarose beads are supplied as a 50% slurry containing 66% glycerol and 4 mg/ml immobilized antibody.
PTM	Succinyl
Modification Site	Lys
Immunogen	Succinylated lysine peptides
Clonality	Polyclonal/Monoclonal
Background	Lysine succinylation is an important reversible modification, and plays significant roles i nmany cellular processes. Systematical screening of lysine succinylated substrates in various cellular pathological and physiological conditions is a fundamental mission in lysine succinylation biology.To address this, the affinity chromatography with Anti-Succinyllysine Antibody Conjugated Agarose Beads followed by MS/MS identification is viewed as the most preferable and efficient method.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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PTM-402-datasheet.pdf

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Amount: 500 ul

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Delivery expected until 11/27/2025

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