Comparison

Human alpha-Smooth Muscle Actin/ACTA2 antibody

Item no. NKM-ATGA0358-100ul
Manufacturer NKMAX
Amount 100 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, FC, ICC, ELISA
Clone AT132D3
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Conjugate/Tag Unconjugated
Citations Herman IM. et al. (1993) Curr Opin Cell Biol. 5(1): 48-55.
Guo DC., et al. (2009) Am J Hum Genet. 84(5): 617-627.
Liu X, et al. Human aortic valve interstitial cells obtained from patients with aortic valve stenosis are vascular endothelial growth factor receptor 2 positive and contribute to ectopic calcification. (J Pharmacol Sci. 2021){https://pubmed.ncbi.nlm.nih.gov/33451756/}
Sakata N, et al. Optimal temperature for the long-term culture of adult porcine islets for xenotransplantation. (Front Immunol. 2023){https://pubmed.ncbi.nlm.nih.gov/37901206/}
Men S, et al. Role of CD34 in calcification of human aortic valve interstitial cells from patients with aortic valve stenosis.(J Pharmacol Sci.2024){https://pubmed.ncbi.nlm.nih.gov/39313278/}
NCBI NP_001604
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Aortic smooth muscle actin,Alpha-actin-2,Cell growth-inhibiting gene 46 protein,Actin,Aortic smooth muscle,Intermediate form,ACTSA,ACTVS,GIG46
Similar products Alpha-actin-2, Actin, ACTSA, ACTVS, GIG46, Cell growth-inhibiting gene 46 protein, Alpha actin 2, Cell growth inhibiting gene 46 protein, Aortic smooth muscle actin, Aortic smooth muscle, Intermediate form, Alpha actin2, ATGA0358-10ug, ATGA0358-20ug, ATGA0358-50ug, ATGA0358-100ug, ATGA0358-250ug, ATGA0358-500ug, ATGA0358-1mg, ATGA0358-010, ATGA0358-020, ATGA0358-050, ATGA0358-100, ATGA0358-250, ATGA0358-500, ATGA0358-01M
Available
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF, FACS
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
Alpha-actin-2 also known as actin, aortic smooth muscle or alpha smooth muscle actin (alpha-SMA, SMactin, alpha-SM-actin, ASMA). Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic beta- and gamma-actin proteins are referred to as non-muscle actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility. Actin has major functions. Firstly, F-actin polymers form microfilaments - polar intracellular tracks for kinesin motor proteins, allowing the transport of vesicles, organelles and other cargo. Actin is a component of the cytoskeleton and links to alpha-actinin, E-cadherin and beta-catenin at adherens junctions. actin has a role in cell motility through polymerization and depolymerization of fibrils.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human ACTA2 (3-377aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-A affinity chromatography
Gene Category
Actin & Myosin Related
Manufacturer - Search Terms
Aortic smooth muscle actin, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, Actin, Aortic smooth muscle, Intermediate form, ACTSA, ACTVS, GIG46, Alpha actin 2, Alpha actin2, Cell growth inhibiting gene 46 protein, ATGA0358-10ug, ATGA0358-20ug, ATGA0358-50ug, ATGA0358-100ug, ATGA0358-250ug, ATGA0358-500ug, ATGA0358-1mg, ATGA0358-010, ATGA0358-020, ATGA0358-050, ATGA0358-100, ATGA0358-250, ATGA0358-500, ATGA0358-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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