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Luminespib (NVP-AUY922)

Luminespib (NVP-AUY922)

Item no.	S1069-100mg
Manufacturer	Selleckchem
CASRN	747412-49-3
Amount	100 mg
Quantity options	10 mg 1 g 10 g 100 mg 10 mM/1 mL 200 mg 25 mg 5 mg 5 g
Category	Oncology Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Neural Signaling Protein Aggregation, Clearance & Misfolding Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Skin Cancer Bladder Cancer Breast Cancer Gastric Cancer
Type	Inhibitors
Specific against	other
Smiles	CCNC(=O)C1=NOC(=C1C2=CC=C(C=C2)CN3CCOCC3)C4=CC(=C(C=C4O)O)C(C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AUY-922,VER-52296
Available
Storage Conditions	2 years -80 in solvent
Information	Luminespib (AUY-922, NVP-AUY922, VER-52296) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1Rβ protein and results in growth inhibition, autophagy and apoptosis. Phase 2.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

S1069-100mg-datasheet.pdf

S1069-100mg-safety-datasheet.pdf