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Flavopiridol (Alvocidib) HCl

Flavopiridol (Alvocidib) HCl

Item no.	S2679-1g
Manufacturer	Selleckchem
CASRN	131740-09-5
Amount	1 g
Quantity options	10 mg 100 mg 10 mM/1 mL 1 g 200 mg 25 mg 50 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Breast Cancer Testicular & Prostate Cancer Brain Cancer
Type	Inhibitors
Specific against	other
Smiles	CN1CCC(C(C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NSC 649890,L86-8275,HMR-1275,DSP-2033
Available
Storage Conditions	2 years -80 in solvent
Information	Flavopiridol (Alvocidib) HCl competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM in cell-free assays. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol HCl induces autophagy and ER stress. Flavopiridol HCl blocks HIV-1 replication. Phase 1/2.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

S2679-1g-datasheet.pdf

S2679-1g-safety-datasheet.pdf