Manufacturer |
St John's Laboratory
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse |
Isotype |
IgG |
Applications |
WB |
Amount |
50ul |
Host |
Rabbit |
Item no. |
STJ114243-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9NZQ8 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15. 5, and has been shown to be imprinted, with exclusive expression from the paternal allele. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1026-1165 of human TRPM5 (NP_055370. 1). |
Short Description |
Rabbit polyclonal against TRPM5 |
Tissue specificity |
Strongly expressed in fetal brain, liver and kidney, and in adult prostate, testis, ovary, colon and peripheral blood leukocytes. Also expressed in a large proportion of Wilms' tumors and rhabdomyosarcomas. In monochromosomal cell lines shows exclusive paternal expression. |
Cellular localization |
Cell MembraneMulti-Pass Membrane Protein |
Molecular weight |
Calculated: 97kDa/131kDa. Observed: 112kDa |
Dilution range |
WB 1:200-1:500 |
Alternative names |
Anti-Transient Receptor Potential Cation Channel Subfamily M Member 5 antibodyAnti-Long Transient Receptor Potential Channel 5 antibodyAnti-Ltrpc-5 antibodyAnti-Ltrpc5 antibodyAnti-Mlsn1-And Trp-Related Gene 1 Protein antibodyAnti-TRPM5 LTRPC5 MTR1 antibody |
Protein name |
Transient Receptor Potential Cation Channel Subfamily M Member 5Long Transient Receptor Potential Channel 5Ltrpc-5Ltrpc5Mlsn1-And Trp-Related Gene 1 Protein |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.