Manufacturer |
St John's Laboratory
|
Category |
|
Type |
Antibody |
Specific against |
Human, Mouse |
Applications |
WB, IF, IHC |
Amount |
50ul |
Host |
Rabbit |
Item no. |
STJ22570-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Description |
The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. |
Short Description |
Rabbit polyclonal to AKR7A2 |
Alternative names |
AKR7A2 antibodyAflatoxin B1 aldehyde reductase member 2 antibodyAKR7A2 antibodyAFAR antibodyAFAR1 antibodyAKR7 antibody |
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Dilution range |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Gene id |
|
Gene symbol |
|
Immunogen |
Recombinant protein of human AKR7A2 |
Iso type |
IgG |
Molecular weight |
39.589 kDa |
Note |
For Research Use Only (RUO). |
Purification |
Affinity purification |
Storage instruction |
Store at -20C. Avoid freeze / thaw cycles. |
Swiss prot key |
|
Tissue specificity |
Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen, Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman's capsules and some cysts, Detected at low levels in lung and pancreas (at protein level), Widely expressed |
Uniprot id |
O43488 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.