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Anti-CASP9 antibody (140-220)

Anti-CASP9 antibody (140-220)

Item no.	STJ92029-100
Manufacturer	St John's Laboratory
Amount	100 ug
Category	Oncology Neuroscience Neural Epigenetics Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Gastric Cancer Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Caspase-9 antibody, Anti-Casp-9 antibody, Anti-Apoptotic Protease Mch-6 antibody, Anti-Apoptotic Protease-Activating Factor 3 antibody, Anti-Apaf-3 antibody, Anti-Ice-Like Apoptotic Protease 6 antibody, Anti-Ice-Lap6 [Cleaved Into-Caspase-9 Subunit P35-Caspase-9 Subunit P10] antibody, Anti-CASP9 MCH6 antibody
Similar products	Anti-Caspase-9 antibody Anti-Casp-9 antibody Anti-Apoptotic Protease Mch-6 antibody Anti-Apoptotic Protease-Activating Factor 3 antibody Anti-Apaf-3 antibody Anti-Ice-Like Apoptotic Protease 6 antibody Anti-Ice-Lap6 [Cleaved Into-C
Available
Storage Conditions	Store at-20°C, and avoid repeat freeze-thaw cycles.
Molecular Weight	46 kDa
Description	Caspase-9 is a protein encoded by the CASP9 gene which is approximately 46, 2 kDa. Caspase-9 is localised to the cytosol, mitochondrion and nucleus. It is involved in the TNFR1 pathway, RET signalling and apoptosis modulation and signalling. Caspase-9 exist as an inactive proenzyme which undergoes proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. It is involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Caspase-9 is ubiquitously expressed with highest expression in the heart. Mutations in the CASP9 gene may result in cerebral hypoxia and cervical cancer. STJ92029 was affinity purified. This poly clonal antibody binds endogenous caspase-9.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	140-220 aa
Tissue specificity	Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.
Clonality	Polyclonal
Protein name	Caspase-9 Casp-9 Apoptotic Protease Mch-6 Apoptotic Protease-Activating Factor 3 Apaf-3 Ice-Like Apoptotic Protease 6 Ice-Lap6 [Cleaved Into-Caspase-9 Subunit P35-Caspase-9 Subunit P10]
Gene symbol	CASP9
Dilution range	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000
Note	For Research Use Only (RUO).
Immunogen Region	140-220 aa
Short Description	Rabbit polyclonal against Caspase-9

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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