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Anti-TP53 antibody

Anti-TP53 antibody

Item no.	STJ98603-100
Manufacturer	St John's Laboratory
Amount	100 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Western Blot ELISA Primary Antibodies Astrocytoma By Organ Lung Cancer Breast Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
Similar products	Cellular tumor antigen p53 Antigen NY-CO-13 Phosphoprotein p53 Tumor suppressor p53
Available
Storage Conditions	Store at-20°C, and avoid repeat freeze-thaw cycles.
Description	Rabbit polyclonal to p53.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	Synthesized peptide derived from synthetic peptide derived from p53.
Tissue specificity	Ubiquitous. Isoforms are expressed in a wide range of normal tissues but in a tissue-dependent manner. Isoform 2 is expressed in most normal tissues but is not detected in brain, lung, prostate, muscle, fetal brain, spinal cord and fetal liver. Isoform 3 is expressed in most normal tissues but is not detected in lung, spleen, testis, fetal brain, spinal cord and fetal liver. Isoform 7 is expressed in most normal tissues but is not detected in prostate, uterus, skeletal muscle and breast. Isoform 8 is detec
Cellular localization	Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment. Isoform 1: Nucleus. Cytoplasm. Predominantly nuclear but localizes to the cytoplasm when expressed with isoform 4.. Isoform 2: Nucleus. Cytoplasm. Localized mainly in the nucleus with minor staining in the cytoplasm.. Isoform 3: Nucleus. Cytoplasm. Localized in the nucleus in most cells but found in the cytoplasm in some cells.. Isoform 4: Nucleus. Cytoplasm. Predominantly nuclear but translocates to the cytoplasm following cell stress.. Isoform 7: Nucleus. Cytoplasm. Localized mainly in the nucleus with minor staining in the cytoplasm.. Isoform 8: Nucleus. Cytoplasm. Localized in both nucleus and cytoplasm in most cells. In some cells, forms foci in the nucleus that are different from nucleoli.. Isoform 9: Cytoplasm.
Clonality	Polyclonal
Protein name	Cellular tumor antigen p53 Antigen NY-CO-13 Phosphoprotein p53 Tumor suppressor p53
Gene symbol	TP53
Dilution range	WB 1:500-2000 ELISA 1:10000-20000
Note	For Research Use Only (RUO).
Short Description	Rabbit polyclonal against p53

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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