Comparison

Anti-LRP6 antibody (200-300) European Partner

Item no. STJ27887-100
Manufacturer St John's Laboratory
Amount 100 ul
Category
Type Antibody Polyclonal
Applications WB
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Storage Conditions
Store at-20°C and avoid freeze-thaw cycles.
Description
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP-(regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Purification
Affinity purification
Immunogen
A synthetic peptide of human LRP6
Clonality
Polyclonal
Dilution range
WB 1:500-1:1000
Note
For Research Use Only (RUO).
Short Description
Rabbit polyclonal against LRP6

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

 
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