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Sitagliptin

Sitagliptin

Item no.	TMO-T0242-10mM
Manufacturer	TargetMol
CASRN	486460-32-6
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg
Category	Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	MK0431
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|Proteasome\|\|\|DPP-4
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	407.31
Description	Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedione for treatment of type 2 diabetes mellitus. The drug can competitively inhibit a protein/enzyme and DPP-4, that leads to an incremental amount of active incretins (GLP-1 and GIP), the diminished amount of release of glucagon and increased release of insulin.
Pathways	Proteases/Proteasome\|\|\|Autophagy\|\|\|Ubiquitination
Formulate	C16H15F6N5O

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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