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Abexinostat

Abexinostat

Item no.	TMO-T0431-2mg
Manufacturer	TargetMol
CASRN	783355-60-2
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9843
Citations	1. Buggy JJ, et al. Mol Y Ther, 2006, 5(5), 1309-1317.
Smiles	CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	CRA 24781,PCI24781,PCI-24781,PCI 24781,CRA 024781
Shipping Condition	Cool pack
Available
Manufacturer - Targets	HDAC
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	397.42
Description	PCI-24781 (Abexinostat (PCI24781)) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.
Pathways	Chromatin/Epigenetic\|\|\|DNA Damage/DNA Repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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