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Methimazole

Methimazole

Item no.	TMO-T0840-25mg
Manufacturer	TargetMol
CASRN	60-56-0
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9994
Citations	1. Sugawara M, et al. Thyroid. 1999 May; 9(5):513-8.
Smiles	CN1C=CN=C1S
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Thiamazole,Tapazole
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Thyroid hormone receptor(THR)
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	114.17
Description	Methimazole (Thiamazole) is an antithyroid compound with significant hepatotoxicity and is often used in the study of hyperthyroidism.
Pathways	Endocrinology/Hormones
Bioactivity	Methimazole is a thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
Receptor	Thyroid peripheral conversion

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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