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Ivermectin

Ivermectin

Item no.	TMO-T1131-1000mg
Manufacturer	TargetMol
CASRN	70288-86-7
Amount	1000 mg
Quantity options	1000 mg 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 20 mg 250 mg 2 g 500 mg 5 g 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Wagstaff KM, et al. Biochem J, 2012, 443(3), 851-856.
Smiles	CO[C@H]1C[C@H](O[C@H]2[C@H](C)O[C@H](C[C@@H]2OC)O[C@H]2[C@@H](C)\C=C\C=C3/CO[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]5C[C@@H](C\C=C2/C)O[C@@]2(CC[C@H](C)[C@H](O2)C(C)C)C5)[C@]34O)O[C@@H](C)[C@@H]1O.CC[C@@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@H](C\C=C(C)\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\C=C\C=C3/CO[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	MK-933
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|GluCls\|\|\|Antibiotic\|\|\|Parasite\|\|\|HIV Protease\|\|\|Mitophagy\|\|\|P2X Receptor\|\|\|HSV\|\|\|SARS-CoV
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	875.09
Description	Ivermectin (MK-933) is an activator of glutamate-gated chloride channels (GluCls) with antiparasitic activity.
Pathways	Membrane transporter/Ion channel\|\|\|Autophagy\|\|\|Neuroscience\|\|\|Microbiology/Virology\|\|\|Proteases/Proteasome
Bioactivity	Ivermectin is a broad-spectrum antiparasitic drug in the avermectin family. It is taken internally or used topically, depending on the treated condition.
Receptor	GluCl channels; P2 receptor

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