Comparison

Gefitinib European Partner

Item no. TMO-T1181-10mM
Manufacturer TargetMol
CASRN 184475-35-2
Amount 1 mL x 10 mM (in DMSO)
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 250 mg 25 mg 500 mg 50 mg 5 g
Category
Type Molecules
Specific against other
Purity 0,98
Smiles N(C=1C2=C(C=C(OC)C(OCCCN3CCOCC3)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias ZD1839
Shipping Condition Cool pack
Available
Manufacturer - Targets
Autophagy|||EGFR|||Tyrosine Kinases
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
446.9
Description
Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation.
Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||Autophagy|||JAK/STAT signaling
Formulate
C22H24ClFN4O3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL x 10 mM (in DMSO)
Available: In stock
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