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Rofecoxib

Rofecoxib

Item no.	TMO-T1185-10mM
Manufacturer	TargetMol
CASRN	162011-90-7
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 2 mg 50 mg
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Aging & Neurological Disorders Enzymes Other Fatty Acid Enzymes Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	O=C1C(=C(CO1)C2=CC=C(S(C)(=O)=O)C=C2)C3=CC=CC=C3
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	MK-0966,MK 966
Shipping Condition	Cool pack
Available
Manufacturer - Targets	COX
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	314.36
Description	Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX-2.
Pathways	Neuroscience\|\|\|Immunology/Inflammation
Formulate	C17H14O4S

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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