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Diacerein

Diacerein

Item no.	TMO-T1273-100mg
Manufacturer	TargetMol
CASRN	13739-02-1
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 50 mg
Category	Neuroscience Neuroinflammation Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Yaron M, et al. Osteoarthritis Cartilage, 1999, 7(3), 272-280.
Smiles	CC(=O)OC1=CC(=CC2=C1C(=O)C1=C(OC(C)=O)C=CC=C1C2=O)C(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Diacerhein,Fisiodar,Diacetylrhein
Shipping Condition	Cool pack
Available
Manufacturer - Targets	IL Receptor\|\|\|Interleukin
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	368.29
Description	Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre diarrhea [L780]. Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications.
Pathways	Immunology/Inflammation
Bioactivity	Diacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.
Receptor	IL-1beta

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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