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(±)-10-Hydroxycamptothecin

(±)-10-Hydroxycamptothecin

Item no.	TMO-T1521-100mg
Manufacturer	TargetMol
CASRN	64439-81-2
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9958
Citations	1. Zhang S, et al. anticancer Drugs. 2014 Jul;25(6):614-23.
Smiles	CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	(±)10Hydroxycamptothecin,(±) 10 Hydroxycamptothecin
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Topoisomerase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	364.35
Description	(±)-10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Pathways	DNA Damage/DNA Repair
Bioactivity	Hydroxy Camptothecine is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Receptor	Topo I

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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