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ADH-1 trifluoroacetate

ADH-1 trifluoroacetate

Item no.	TMO-T1608-10mg
Manufacturer	TargetMol
CASRN	1135237-88-5
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1.Perotti A, et al. Ann Oncol. 2009 Apr;20(4):741-5.
Smiles	OC(=O)C(F)(F)F.CC(C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(N)=O)NC(C)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Exherin trifluoroacetate
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Dehydrogenase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	684.71
Description	ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis.
Pathways	Metabolism

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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