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Tandutinib

Tandutinib

Item no.	TMO-T1667-50mg
Manufacturer	TargetMol
CASRN	387867-13-2
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Signaling Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Molecules
Specific against	other
Citations	1. Kelly LM, et al. Y Cell, 2002, 1(5), 421-432.
Smiles	O(C)C1=CC=2C(=NC=NC2C=C1OCCCN3CCCCC3)N4CCN(C(NC5=CC=C(OC(C)C)C=C5)=O)CC4
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	MLN518,CT53518,NSC726292
Shipping Condition	Cool pack
Available
Manufacturer - Targets	CSF-1R\|\|\|Src\|\|\|PDGFR\|\|\|c-Kit\|\|\|Apoptosis\|\|\|FLT
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	562.7
Description	Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
Pathways	Angiogenesis\|\|\|Apoptosis\|\|\|Tyrosine Kinase/Adaptors

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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