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Genistein

Genistein

Item no.	TMO-T1737-1000mg
Manufacturer	TargetMol
CASRN	446-72-0
Amount	1000 mg
Quantity options	1000 mg 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Neural Signaling Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Molecules
Specific against	other
Citations	1. Akiyama T, et al. J Biol Chem, 1987, 262(12), 5592-5595.
Smiles	OC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	NPI 031L
Shipping Condition	Cool pack
Available
Manufacturer - Targets	EGFR\|\|\|Apoptosis\|\|\|Endogenous Metabolite\|\|\|Autophagy
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	270.24
Description	Genistein (NPI 031L) is a naturally occurring soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor, antioxidant, and anthelmintic properties, and also produces estrogen-like effects in the body.
Pathways	Metabolism\|\|\|Angiogenesis\|\|\|Tyrosine Kinase/Adaptors\|\|\|Autophagy\|\|\|Apoptosis\|\|\|JAK/STAT signaling
Bioactivity	Genistein(NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12uM or by insulin with IC50 of 19 uM.
Receptor	EGFR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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