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Obeticholic Acid

Obeticholic Acid

Item no.	TMO-T1789-200mg
Manufacturer	TargetMol
CASRN	459789-99-2
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Pellicciari R, et al. J Med Chem. 2002, 45(17), 3569-3572.
Smiles	CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(O)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	INT-747,6-Ethylchenodeoxycholic acid,6-ECDCA
Shipping Condition	Cool pack
Available
Manufacturer - Targets	FXR\|\|\|Autophagy
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	420.63
Description	Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist with an EC50 of 99 nM and is able to upregulate IκB-α, KLF-2, and KLF-4 expression. Obeticholic Acid (6-ECDCA, INT-747) also shows potential for treating hepatic steatosis, inflammation, and fibrosis while increasing insulin sensitivity.
Pathways	Metabolism\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 mg

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