Comparison

Rac-Belinostat European Partner

Item no. TMO-T1852-100mg
Manufacturer TargetMol
CASRN 414864-00-9
Amount 100 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 20 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Purity 0,98
Smiles ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1ccccc1
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias NSC726630,PXD101,PX-105684
Similar products 414864-00-9
Shipping Condition Cool pack
Available
Manufacturer - Targets
HDAC
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
318.35
Description
Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
available

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