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Dinaciclib

Dinaciclib

Item no.	TMO-T1912-100mg
Manufacturer	TargetMol
CASRN	779353-01-4
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Neuroscience Neural Signaling Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Wei Fu, et al. Molecular Y Therapeutics (2011), 10(6), 1018-1027.
Smiles	N(CC1=CN(=O)=CC=C1)C=2N3C(N=C(C2)N4[C@H](CCO)CCCC4)=C(CC)C=N3
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	SCH 727965,PS-095760
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	396.49
Description	Dinaciclib (SCH 727965) is a selective CDK inhibitor targeting CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM). It exhibits potential antitumor activity by inhibiting the incorporation of thoracic glycan (dThd) DNA.
Pathways	Cell Cycle/Checkpoint\|\|\|Apoptosis
Bioactivity	Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.
Receptor	CDK1; CDK2; CDK5; CDK9

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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