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NVP-TAE 226

NVP-TAE 226

Item no.	TMO-T1918-1ml
Manufacturer	TargetMol
CASRN	761437-28-9
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	TAE226
Similar products	761437-28-9
Shipping Condition	Cool pack
Available
Manufacturer - Targets	c-Met/HGFR\|\|\|FAK\|\|\|Apoptosis\|\|\|PYK2\|\|\|IGF-1R
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	468.94
Description	NVP-TAE 226 (TAE226) is a potent FAK inhibitor (IC50: 5.5 nM), exhibiting even greater efficacy against Pyk2 (IC50: 3.5 nM), and is 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.
Pathways	Cytoskeletal Signaling\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis\|\|\|Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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