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AZD-3463

AZD-3463

Item no.	TMO-T1967-2mg
Manufacturer	TargetMol
CASRN	1356962-20-3
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Reagents & Chemicals Molecules By Organ Colorectal Cancer
Type	Molecules
Specific against	other
Citations	1. 104th AACR meeting, 2013, Abst 919.
Smiles	COc1cc(ccc1Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12)N1CCC(N)CC1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	ALK/IGF1R inhibitor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|ALK\|\|\|Autophagy\|\|\|IGF-1R
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	448.95
Description	AZD-3463 (ALK/IGF1R inhibitor), an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.
Pathways	Tyrosine Kinase/Adaptors\|\|\|Apoptosis\|\|\|Autophagy\|\|\|Angiogenesis
Bioactivity	AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency.
Receptor	ALK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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