PFI-2

Item no.	TMO-T1987-100mg
Manufacturer	TargetMol
CASRN	1627676-59-8
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9991
Citations	1. Barsyte-Lovejoy D, et al. Proc Natl Acad Sci U S A. 2014, 111(35), 12853-12858.
Smiles	FC1=C2C(=CC(S(N[C@H](CC3=CC(C(F)(F)F)=CC=C3)C(=O)N4CCCC4)(=O)=O)=C1)CCNC2
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PFI2,PFI 2,(R)-PFI-2
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Histone Methyltransferase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	499.52
Description	PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
Pathways	Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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