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JANEX-1

JANEX-1

Item no.	TMO-T2045-100mg
Manufacturer	TargetMol
CASRN	202475-60-3
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9821
Citations	1. Sudbeck EA, et al. Clin Y Res. 1999 Jun;5(6): 1569-82.
Smiles	COc1cc2ncnc(Nc3ccc(O)cc3)c2cc1OC
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Jak3 inhibitor I,WHI-P131
Shipping Condition	Cool pack
Available
Manufacturer - Targets	JAK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	297.31
Description	JANEX-1 (Jak3 inhibitor I) is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 μM); little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases.
Pathways	Angiogenesis\|\|\|Chromatin/Epigenetic\|\|\|Tyrosine Kinase/Adaptors\|\|\|JAK/STAT signaling\|\|\|Stem Cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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