LCL161

Item no.	TMO-T2080-50mg
Manufacturer	TargetMol
CASRN	1005342-46-0
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Breast Cancer
Type	Molecules
Specific against	other
Purity	0,98
Smiles	CNC(C)C(=O)NC(C1CCCCC1)C(=O)N1CCCC1c1nc(cs1)C(=O)c1ccc(F)cc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	LCL161,LCL-161,LCL 161,IAP inhibitor
Similar products	1005342-46-0
Shipping Condition	Cool pack
Available
Manufacturer - Targets	IAP
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	500.63
Description	LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP (IC50=35 nM) in HEK293 cells and also inhibits cIAP1 (IC50=0.4 nM) in MDA-MB-231 cells. LCL161 has potential antitumor activity.
Pathways	Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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