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cis-NVP-ADW742

cis-NVP-ADW742

Item no.	TMO-T2107-10mM
Manufacturer	TargetMol
CASRN	475489-15-7
Amount	1 mL x 10 mM (in DMSO)
Quantity options	1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Heart & Blood Cancer
Type	Molecules
Specific against	other
Citations	1. Mitsiades CS, et al. Y Cell, 2004, 5(3), 221-230.
Smiles	NC1=C2C(N([C@@H]3C[C@@H](C3)CN4CCCC4)C=C2C5=CC(OCC6=CC=CC=C6)=CC=C5)=NC=N1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	IGF-1R inhibitor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	IGF-1R
Storage Conditions	-20
Molecular Weight	453.59
Description	NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
Pathways	Tyrosine Kinase/Adaptors
Bioactivity	NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 uM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
Receptor	IGF-1R

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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