Comparison

(+)-JQ-1 European Partner

Item no. TMO-T2110-1ml
Manufacturer TargetMol
CASRN 1268524-70-4
Amount 1 mL
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Chemicals
Specific against other
Formula C23H25ClN4O2S
Smiles CC=1C2=C(N3C([C@H](CC(OC(C)(C)C)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)SC1C
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Alias JQ1
Similar products 1268524-70-4
Shipping Condition Cool pack
Available
Manufacturer - Targets
Ligands for Target Protein for PROTAC|||Autophagy|||Epigenetic Reader Domain
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
456.99
Description
(+)-JQ-1 (JQ1) is a specific, reversible BET bromine domain inhibitor that targets BRD4 (1/2) with IC50 values of 77/33 nM. (+)-JQ-1 induces cell autophagy and inhibits cell proliferation.
Pathways
PROTAC|||Chromatin/Epigenetic|||Autophagy
Bioactivity
(+)-JQ1 is a BET bromodomain inhibitor (IC50: 77 nM/33 nM for BRD4 (1/2)).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL
Available: In stock
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