WP1066

Item no.	TMO-T2156-10mg
Manufacturer	TargetMol
CASRN	857064-38-1
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 500 mg 50 mg 5 mg
Category	Neuroscience Neural Lineage Markers Neural Transcription Factors Neural Signaling Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	C[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	WP1066,WP 1066,WP-1066,JAK inhibitor,STAT inhibitor
Similar products	857064-38-1
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|STAT\|\|\|JAK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	356.22
Description	WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.
Pathways	Apoptosis\|\|\|Chromatin/Epigenetic\|\|\|Tyrosine Kinase/Adaptors\|\|\|JAK/STAT signaling\|\|\|Stem Cells\|\|\|Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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