Comparison

Icotinib Hydrochloride European Partner

Item no. TMO-T2307-10mM
Manufacturer TargetMol
CASRN 1204313-51-8
Amount 1 mL x 10 mM (in DMSO)
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Purity 0,98
Smiles Cl.C#Cc1cccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)c1
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias BPI-2009H
Shipping Condition Cool pack
Available
Manufacturer - Targets
EGFR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
427.88
Description
Icotinib Hydrochloride (BPI-2009H) is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of EGFR, with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types.
Pathways
Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis
Formulate
C22H22ClN3O4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL x 10 mM (in DMSO)
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close