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CHIR-99021

CHIR-99021

Item no.	TMO-T2310-5mg
Manufacturer	TargetMol
CASRN	252917-06-9
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	Cc1c[nH]c(n1)-c1cnc(NCCNc2ccc(cn2)C#N)nc1-c1ccc(Cl)cc1Cl
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Laduviglusib,CT99021,CHIR-99021
Similar products	252917-06-9
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GSK-3\|\|\|Autophagy\|\|\|Wnt/beta-catenin
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	465.34
Description	CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells.
Pathways	Cytoskeletal Signaling\|\|\|Stem Cells\|\|\|PI3K/Akt/mTOR signaling\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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