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KW-2449

KW-2449

Item no.	TMO-T2341-10mM
Manufacturer	TargetMol
CASRN	1000669-72-6
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Signaling Reagents & Chemicals Molecules By Organ Heart & Blood Cancer
Type	Molecules
Specific against	other
Purity	0,98
Smiles	O=C(N1CCNCC1)c1ccc(C=Cc2n[nH]c3ccccc23)cc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	KW2449
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Src\|\|\|JAK\|\|\|c-Kit\|\|\|FLT\|\|\|Apoptosis\|\|\|FGFR\|\|\|Bcr-Abl\|\|\|Aurora Kinase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	332.4
Description	KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 (IC50: 6.6 nM), modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.
Pathways	Angiogenesis\|\|\|Cell Cycle/Checkpoint\|\|\|Stem Cells\|\|\|Apoptosis\|\|\|Cytoskeletal Signaling\|\|\|JAK/STAT signaling\|\|\|Tyrosine Kinase/Adaptors\|\|\|Chromatin/Epigenetic
Formulate	C20H20N4O

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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