« Back
Home /
Rociletinib

Rociletinib

Item no.	TMO-T2369-500mg
Manufacturer	TargetMol
CASRN	1374640-70-6
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Signaling Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Molecules
Specific against	other
Citations	1. Walter AO, et al. Y Discov. 2013 Sep 25.
Smiles	COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	AVL-301,CNX-419,CO-1686
Shipping Condition	Cool pack
Available
Manufacturer - Targets	EGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	555.55
Description	Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity.
Pathways	Angiogenesis\|\|\|Tyrosine Kinase/Adaptors\|\|\|JAK/STAT signaling
Bioactivity	CO-1686 is a novel, irreversible and orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M(IC50=21 nM).
Receptor	EGFR (L858R/T790M); EGFR (wt)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T2369-500mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 500 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question