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Pirfenidone

Pirfenidone

Item no.	TMO-T2386-1000mg
Manufacturer	TargetMol
CASRN	53179-13-8
Amount	1000 mg
Quantity options	1000 mg 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 25 mg 500 mg 50 mg 5 g
Category	Metabolism Diabetes Glucose Homeostasis Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Nakazato H, et al. Eur J Pharmacol, 2002, 446(1-3), 177-185.
Smiles	O=C1N(C=C(C)C=C1)C2=CC=CC=C2
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	S-7701,AMR-69,S-7701,AMR69
Shipping Condition	Cool pack
Available
Manufacturer - Targets	CCR\|\|\|TGF-beta/Smad
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	185.22
Description	Pirfenidone (AMR69) inhibits the production of CCL2 and CCL12 in fibroblasts and also decreases TGF-β2 protein levels. Pirfenidone is an antifibrotic agent that is commonly used in studies related to pulmonary fibrosis and also has anti-inflammatory activity.
Pathways	Microbiology/Virology\|\|\|Stem Cells\|\|\|Immunology/Inflammation\|\|\|GPCR/G Protein
Bioactivity	Pirfenidone is an inhibitor for?TGF-beta?production and TGF-beta stimulated collagen production, reduces production of?TNF-alpha?and IL-1beta, and also has anti-fibrotic and anti-inflammatory properties. Phase 3.
Receptor	TGFbeta2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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